What does nested cross-validation estimate?

A researcher performs hyperparameter selection using inner cross-validation and reports the average score from an independent outer cross-validation loop. What does the outer-loop score most directly estimate?

A

An unbiased estimate of the Bayes error whenever the outer folds are stratified

B

The expected performance of every hyperparameter configuration considered in the inner loop

C

The generalization error of the model refitted once on the complete dataset using the globally best hyperparameters

D

The generalization performance of the full model-selection procedure, including hyperparameter tuning